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C4D

Centre for Drug Design Discovery and Development (C4D) is established at SRMUH to initiate drug discovery projects focusing on neglected infectious diseases with national and international collaborations. The centre has the infrastructural facilities for drug discovery, developing diagnostic kits and tackling antimicrobial resistance. At present the centre has many projects funded by various Government funding agencies, such as, DBT, ICMR, DSIR, SERB, DST, etc.

The objectives of the centre are to

  • Discover new drugs against neglected and emerging infectious diseases such as Tuberculosis, dengue chikungunya, kala azar, malaria, meningitis, diarrheal diseases and other neglected diseases caused by parasites, virus and gram-negative pathogens. Synergy studies with existing FDA approved drugs and formulation development as well as using nanotechnology to overcome toxicity issues.
  • Exploring natural products as a source of antibiotics, and plant/ herbal extracts as a source of treatment.
  • Discovering new chemical entities using focused chemical library and fragment based drug discovery.
  • Re-purposing of drugs for the improvement of treatment against Visceral Leishmaniasis with the aim of averting the emergence of PKDL.
  • Surveillance of antimicrobial resistance to monitor the emergence of multi-drug resistance in pathogens causing serious infections.
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